Klinicheskaya Laboratornaya Diagnostika №9 2012

CONTENTS

THE ACTUAL ORGANIZATIONAL ECONOMIC ISSUES OF LABORATORY SUPPORT OF MEDICAL CARE

 
Zheleznyakova I.A. The implementation of payment modes oriented to the result of activity of medical organizations in the subjects of the Russian Federation 4
Menshikov V.V. On the change of paradigms of the organization of medical care laboratory support 4

THE ISSUE PUBLICATIONS

 
Grischenko D.A., Tkatchenko O.A. The organization of infectious security of laboratory support of patients and personnel in the newly started medical institution 5
Dvorkin V.I. The computerization of laboratories: SControl block 6
Kostin G.M., Tolkatchev A.V., Sykalo V.I. The actual clinical laboratory directions in ambulatory practice 6
Kulakova S.G. The enhancement of quality of laboratory service of population in the conditions of municipal polyclinic 6
Menshikov V.V. The portative analytical devices as a tool enhancing the availability of laboratory analysis in the primary medical care 6
Miroshnitchenko I.A., Skvortsova R.G., Ushakov I.V. The elements of improvements in the clinical diagnostic laboratory on the basis of modern technologies of management 7
Ustyantseva I.M., Khokhlova O.I. The laboratory analysis support of multilevel medical care 7
Filippova N.V., Imelbayeva E.A., Gilmanov A.J. On the activity of municipal laboratory of AIDS diagnostics in the new organizational economic conditions 7

THE ECONOMIC EFFECTIVENESS OF LABORATORY SERVICE

 
Sochkova L.V., Morozova M.G., Berestovskaya V.S. The financial risk of laboratory activity in the mandatory medical insurance system 8
Pavlushkina L.V., Potapova T.V. The attempt of evaluation of the ratio of laboratory analyses cost price and mandatory medical insurance standard tariff s of Moscow according to ICD-10 nosology forms 8
Reznitchenko M.F., Ostrovsky O.V., Verovsky V.G., Zaytsev V.G., Dudtchenko G.P., Dyatchenko T.S. The algorithm of carrying out the clinical economic analysis of laboratory tests to confi rm diagnosis 9
Sochkova L.V., Morozova M.G., Berestovskaya V.S. The economic expedience of service rendering by centralized laboratory 9
Dolgikh T.I., Tirskaya Yu.I., Belkova T.N. The calculation of clinical economic effectiveness of the modified algorithm of examination of pregnant women for prenatal infections 9
Fedorenko A.S., Burbello A.T., Gaykovaya L.B. The clinical economic expedience of immunological analysis in patients with chronic inflectional inflammatory diseases 9
Barantseva L.F., Yeganova S.P., Suplotov S.N. On the optimization of estimated time rate in laboratory analysis in clinical diagnostic laboratory 10

THE ISSUE PUBLICATIONS

 
Olkhovsky I.A. The cloud integration: laboratory information system, medical information system, family doctor and patients’ money 10
THE QUALITY OF ANALYSES AND MEASUREMENTS IN LABORATORY MEDICINE  
Kishkun A.A., Arsenin S.L. The support of metrological requirements in clinical laboratory diagnostics: necessity and reality 11
Ostrovsky O.V., Verovsky V.Ye., Bondarev A.M., Dudtchenko G.P., Lutchinin D.N., Diyatchenko T.S., Dyuka Ye.V. The quantitative evaluation of measurements’ quality in clinical diagnostic laboratory 12
Boldyriev I.V., Yeroshina O.V. The accreditation of clinical diagnostic laboratories 12
Pervushin Yu.V., Bondareva V.P., Rogova S.Sh., Golubeva I.F., Privalova L.V., Makarova D.V., Obryadina A.P., Ulanova T.I. The results of external evaluation of quality of diagnostic of HBsAg using the immune enzymatic analysis technique in the laboratories of Stavropol kray on the test-systems manufactured by the R&D production facility «diagnostic systems» 12
Guseva S.L., Gorokhova I.V., Vorobyeva M.P. The role of the Federal system of quality control in enhancement of quality of clinical laboratory analyses 13
Kazakova M.S., Lugovskaya S.A., Dolgov V.V. The reference values of indicators of leukogram in adults 13

THE STANDARDS AND PRACTICE OF LABORATORY SUPPORT OF MEDICAL CARE

 
Gylmiyarova F.N., Gusyakova O.A., Selezneva I.A., Sidorova I.F. The modern laboratory standards in practice of the regional clinical laboratory service 13
Kulyutsyna Ye.R. The implementation of regional standards of medical care in the conditions of clinical diagnostic laboratory of central district hospital 13
Bazarny V.V., Bessonova Ye.N., Garenskikh N.V. The possibilities of actual standard of care of patients with hepatocirrhosis and real needs of clinical practice 14
Glybotchko P.V., Zakharova N.B., Ponukalin A.N., Rossolovsky A.N., Varaksin N.A., Dolgov A.B. The prospects of inclusion of «urinal» markers to laboratory examination standards in case of exacerbation of chronic pyelonephritis 14
Yejikova A.V., Gudskov O.N., Andreyeva O.V. The results of application of biochemical analyses in the framework of population target dispensaryzation program on the base of municipal polyclinic 15
Gylyazova G.G., Galymova R.G., Imelbayeva E.A., Sultanbayev U.S., Stepanova V.T., Gilmanov A.J. On the activities of immunological department of the Republic station of blood transfusion in new conditions 15
Gatin A.V., Kulyutsyna Ye.R., Moiseyenko V.A. The evaluation of content of clinical laboratory examination of traumatology patients with high risk of venous thromboemboliс complications 16
Simonova I.A., Pitchkovskaya V.A., Burenina N.Yu., Kubanov A.A., Frigo N.V. The laboratory support of standards of medical care rendering to patients with psoriasis and atopic dermatitis 16

THE ISSUE PUBLICTIONS

 
Gelman Ye.A., Andryukov B.G., Sidorenko N.P. The role of cystatin C in laboratory strategies under chronic renal diseases: the harmonization of national guidelines with international manuals 17
Gusyakova O.A., Selezneva I.A., Yepifanova A.A., Kolsanov A.V. The guidelines on development of standard of preparation of patient for surgery in case of kidney transplantation 17
Gutchetl Ye.V., Ponomareva L.P., Pushkina T.N., Sokol L.A., Shevtchenko N.P. The application of national standards of laboratory medicine in work of clinical diagnostic laboratory 17
Dorn O.Yu., Stepanova Ye.G., Palamartchuk M.V., Tsykalenko Ye.A., Anikina T.V. The analysis of content of free light chains of immunoglobulin in blood serum of patients with monoclonal gammopathies in concordance with actual standards of laboratory medicine 18
Komarova I.N. The lower level of diagnostics and monitoring of malignant gammopathies. Three components of the problem: knowledge, laboratory support, tariffs 18
Mavzyutov A.R. On the issue of laboratory services goodness to the adopted procedures of medical care rendering in case of viral infections and to the actual standards of laboratory medicine 18
Pozdnyakov S.V., Alekseyeva A.A. The laboratory services goodness to the actual guidelines on control of psychotropic agents’ therapy in hospital conditions 19
Sosnin D.A., Kirillov O.V., Tolkunov V.I., Alifanov S.A., Ostrovsky O.V. The renal enzymes activity in urine in patients with chronic urinary retention 19

THE STANDARDIZATION OF TECHNOLOGY OF IMMUNE PHENOTYPING OF LYMPHOCYTES USING THE FLOW CYTOMETRY TECHNIQUE

 
Khaidukov S.V. The standardizations of the flow cytometry technique for immune phenotyping: the regulations of preparation of protocols and tuning of cytometers for analysis 20
Serebrovskaya L.V., Khaydukov S.V. The standardization of pre-analytical stage 20
Zurotchka A.V., Mhaydukov S.V.Maratcheva N.M., Zurotchka V.A., Khaydukov S.V. The clinical significance of determination of small subpopulations of lymphocytes 20

THE ACTUAL APPROACHES TO EARLY DIAGNOSTIC OF CANCER OF PROSTATE GLAND

 
Govorov A.V. The international experience of applying the test of detection of prostate specific antigen (PSA) for the purpose of early diagnostic of cancer of prostate gland 21
Lazzeri M., Lughezzani G., Lista G., Larcher A., Gadda G.M., Guazzoni G. The recent data of using the new marker of cancer of prostate gland [-2] proPSA and prostate health index (PHI) 21
Rujanskaya A.V., Yevgina S.A. The standardization of detection of prostate specific antigen (PSA): the practical value for laboratory and clinical physicians 21
Peshkov M.N. The post-genome technologies in diagnostic of cancer of prostate Gland 21

THE DEVELOPMENT OF LABORATORY ANALYTICS

 
Kubanova A.A., Kubanov A.A., Frigo N.V., Khairullin R.F., Rotanov S.V. The development of chip to diagnose syphilis using simultaneous detection of antibodies to cardiolipin and specific antigens T. Pallidium 22
Timtchenko N.F., Rayev M.B., Andryukov B.G., Nedashkovskaya Ye.P., Persiyanova Ye.V. The economic, fast and without instruments detection of antibodies to Yersinia pseudotubrerculosis using the test system designed on the basis of conjugate carbon nanoparticles in the format of immune membrane technologies 22
Dolgushin I.I., Savotchkina A.Yu., Shishkova Yu.S., Smirnova T.G., Pegushina I.V., Markova V.A., Baturina I.L. The technique of detection of neutrophil extracellular traps in cervical secretion 23
Dombrovsky V.S., Panyukov Ye.V. The innovative optical (without electrode) technology for mobile express-diagnostic of critical conditions 23
Gorshkova M.A., Lapina G.P., Pankrushina A.N. The express technique of quantitative detection of total graining and urease activity of urine with the purpose to apply in screening examinations to diagnose urolithiasis 23
Kishkun A.A., Arsenin S.L., Kondratyeva K.F. The current condition and new recommendations on testing glycated hemoglobin 24
Komarova I.N. The evaluation of widespread methods of analysis of glycated hemoglobin HbA1с goodness to requirements of International federation of clinical chemistry (IFCC) 24
Ivashikina T.M., Berestovskaya V.S., Kotova T.N., Pashkova V.P. The consideration of acceptability of method of detection of glycated hemoglobin using the analyzer Cobas c501 in assessing the effectiveness of treatment under diabetes mellitus 24
Sergeyevitchev D.S., Subbotovskaya A.I., Kozyreva V.S., Shilova A.N. The development of diagnostic test system of polymerase chain reaction analysis of mutations of cytochrome P450 (CYP2C19) for individual selection of dose of clopydogrel 25

THE ISSUE PUBLICATIONS

 
Agafonov V.A. The mode of target marking of informative site of cytological preparation 25
Bondar T.P., Elkanova A.B.,Meltchenko Ye.A. The application of scanning probe microscopy of eosinophils in diagnostics of eosinophilia of infection allergic genesis 25
Botvitch Yu.A., Baron A.V., Olkhovsky I.A., Baron I.I., Puzyr A.P., Bondar V.S. The impact of modified nano diamonds of detonation synthesis on protein fractions of blood 26
Dolgushin I.I., Savotchkina A.Yu., Abramovskyh O.S., Smirnova T.G., Pegushina I.V., Markova V.A., Kurnosenko I.V. The method of detection of neutrophil extracellular traps under septic states 26
Lakhtin V.M., Lakhtin M.V., Afanasyev S.S., Aleshkin V.A. The chemoluminescent monitoring of excretion of human recombinant erythropoietin with urine 26
Medovy V.S. The robotized microscopy and information technologies increase the sensitivity ТВ availability of techniques of analysis of morphology of blood cells 27
Navolnev S.O. The development of computer program to analyze the 3D image received using microscope 27
Timtchenko N.F., Andryukov B.G., Nedashkovskaya Ye.P., Persiyanova Ye.V. The species-specific solid-phase immune enzyme test system to detect antibodies to Yersinia pseudotuberculosis in human blood serum 27

THE LABORATORY MARKERS IN CARDIOLOGY

 
Kopylov F.Yu. The biomarkers in cardiologic practice 28
Velkov V.V. The highly sensitive cardiomarkers: the reclassification of cardiovascular risks 28
Sheshurina T.A., Dorofeykov V.V., Ivanov V.I., Kurapeyev D.I., Kabanov V.O., Grebennik V.K. The comparative analysis of dynamics of troponin I and T under carrying out the coronary artery bypass grafting in patients with ischemic heart disease 29
Demidova V.S., Khusnetdinova A.U., Pivovarova Ye.M., Kutcheynik A.Sh., Tsygankov V.N., Gontcharov A.I., Nesuk O.M., Nikolayeva O.N., The protein C in the anti-inflammatory mechanism under endovascular treatment of ischemic heart diseased 29
Leschenko I.J., Vorobiyev R.I. The function of endothelium monolayer under diseases of blood circulation system 29
Yegorova Ye.N., Mazur V.V., Gorshkova M.A. The relationship of levels of NH2-terminal brain natrium uretic propeptid and endotoxemia under chronic cardiac insufficiency 30
Guriyanova S.A., Zakharova N.B., Nikitina V.V., Grishanina T.V., Glushatch I.A. The significance of detection of cardio-markers on the stage of hospitalization into cardio-surgery hospital 30
Terekhina N.A., Goryatcheva O.G., Anisimov G.V., Orbidans A.G., Terekhin G.A. Then prognostic significance of detection of activity of gammaglutamyltranspeptodase in biological liquids under terminal states 30

THE ISSUE PUBLICATIONS

 
Bublikov D.S., Andriyenko A.V., Piyanzin A.I., Dadey A.N. C-reactive protein: a routine standard of examination of patients of rheumatologic profile or marker of cardio-vascular disease? 31
Bublikov D.S., Vorobyeva Ye.N. The concentration of tiobarbiturate active products in blood serum as a golden standard of diagnostics of oxidative stress 31
Vorobyeva Ye.N., Leschenko I.J., Simonova O.G., Karbyshev A.I., Barybin A.M., Valova A.G., Nazartchuk Ye.A., Yepantchintseva L.V. The disorders of lipid metabolism under ischemic heart disease 31
Vorobyeva Ye.N., Sokolova G.G., Kazyzayeva A.S., Yefremushkina A.A., Bublikov D.S. The resistance to oxidation of lipoproteins of low density under cardio-vascular diseases 31
Zavarin V.V., Radkov O.V. The prognostic significance of level of fetal extracellular DNA in blood plasma of pregnant women with chronic arterial hypertension 32
Zanina Ye.V., Tchistyakova G.N. The evaluation of indicators of reninangiotensin-aldosterone system in newborns of women with chronic arterial hypertension 32
Ilytcheva O.Ye., Kharlamova U.V. The relationship of laboratory markers of phosphorus calcium metabolism and structural functional indicators of myocardium in patients passing hemodialysis 32
Kaystrya I.V., Dorofeykov V.V., Rotar O.P., Konrady A.O. The disorders of lipid metabolism in males of the North-West region of Russia. What changed after 40 years? 33
Kosmatcheva Ye.D., Vasiltcheva J.M., Tchuprinenko L.M., Slavinsky A.A. The level of activation of neutrophil leucocytes in patients with acute coronary syndrome 33
Nikitina V.V., Zakharova N.B., Burov Yu.A. The perspective of inclusion the molecular markers into standards of examination of patients with arteriosclerosis obliterans of vessels of lower extremities 33
Slavinsky A.A., Kosmatcheva Ye.D., Vasyltcheva J.M., Tchuprinenko L.M. The indicator of neutrophilia in forecasting acute coronary syndrome outcomes 34
Subbotovskaya A.I., Sergeyevitchev D.S., Kozyreva V.S., Shylova A.N., Grajdankin I.O., Osiyev A.G. The rate of polymorphism of CYP2C19*2, CYPP219*3 and CYP2C19*17 genes in patients with acute myocardium infarction 34
Kharlamova U.V., Ilytcheva O.Ye. The new biomarkers of risks of cardiovascular complications in patients on hemodialysis 34
Sharlayeva Ye.A., Vorobyeva Ye.N., Sokolova G.G. The hypercholesterolemia in different age and gender groups 34
Sheshurina T.A., Dorofeykov V.V., Kurapeyev D.I., Shabanova G.R., KabanovV.O., Grebennik V.K. Troponin I under coronary artery bypass grafting in early post operation period: the methodic issues of detection 35

THE RUSSIAN REALITIES AND CHARACTERISTICS OF ORGANIZATION OF LABORATORY EXPRESS DIAGNOSTICS

 
Klytchnikova Ye.V. The laboratory express-diagnostics in urgent profile surgery hospital. The experience of the N.V. Sklyfosofsky Research institute of emergency care 35
Dementiyeva I.I. The organization of laboratory express diagnostics in multitype surgery hospital 35
Benevolensky D.S. The biomarkers in express diagnostics of emergency states 36
Kishkun A.A., Arsenin S.L. The laboratory diagnostics of emergency states from the positions of evidence medicine 37

THE CONSISTENT APPROACH TO OPTIMIZATION AND AUTOMATION OF LABORATORY PROCESSES

 
Ostrovsky V.B., Sveschinsky M.L., Moshkin A.V., Panna V. The consistent approach to optimization and automation of laboratory processes 38

THE IMMUNOLOGIC RESEARCH IN LABORATORY PRACTICE

 
Novikov A.A., Tcherkasova M.V., Aleksandrova Ye.V., Karateyev D.Ye., Popkova T.V., Lutchikhina Ye.L., Lukina G.V., Nasonov Ye.L. The diagnostic value of detection of autoantibodies to citrullinated proteins under rheumatoid arthritis: the new data 38
Aleksandrova Ye.N., Avdeyeva A.S., Novikov A.A., Tcherkasova M.V., Nasonov Ye.L. The role of antibodies to citrullinated modified vimentin in prognosis of response to therapy with gene engineering biological preparatio 38
Guseva I.A., Soroka N.Ye., Lutchikhina Ye.L., Demidova N.V., Panasyuk Ye.Yu., Novikov A.A., Aleksandrova Ye.N., Samarkina Ye.Yu., Fedorenko Ye.V., Devyataykina A.Yu., Gubar Ye.Ye., Tsvetkova Ye.S., Gavva T.N., Avdeyeva A.S., Pozdnyakova Ye.S., Lukina G.V., Karateyev D.Ye., Trofi mov D.Yu., Nasonov Ye.L. The genetics of rheumatoid arthritis: the significance of genetic markers in susceptibility of disease development, prognosis of disease course and eff ectiveness of therapy 39
Tcherkasova M.V., Novikov A.A., Aleksandrova Ye.N., Karateyev D.Ye., Popkova T.V., Lutchikhina Ye.L., Lukina G.V., Nasonov Ye.L. The detection of antibodies to citrullinated proteins using the technique of indirect immunofluorescence under rheumatoid arthritis 39
Zayko S.D. The possibilities of modern clinical diagnostic laboratory in diagnostics of actual autoimmune pathologies 39

The ISSUE PUBLICATIONS

 
Aleksankin A.P., Aleksandrova Ye.P., Avdeyeva A.S., Tzanyan M.E., Tcherkasova M.V. The depletion of b-cells against the background of Rituximab therapy in patients with rheumatoid arthritis and systemic lupus erythematous 40
Ardatova L.V., Kravetz A.A., Slavogorodsky V.S. The antibodies to DNA in patients with rheumatoid arthritis 40
Batanina I.A., Vorobyeva Ye.N., Zalzman A.G., Podyapolskaya I.A., Kondakova N.V., Skovorodnikova M.A., Sharapov V.A., Fugol D.S. The diagnostics of celiac disease 40
Vasneva J.P., Bothckareva N.N. The evaluation of sensitization to iodinated contrast agents 41
Vasneva J.P., Kuznetsova T.L. The levels of specific antibodies to pharmaceuticals 41
Vasneva J.P., Yasko I.G., Beliyayeva L.V. The specific immunity in patients with occupational allergy 41
Gaziyeva I.A. The prognostic value of regulators of functional condition of endothelium in evaluating the risk of placental insufficiency development 41
Garypova Z.P., Shamylov R.R., Garypov R.M., Gilmanov A.J. The prognostic Vlue of immunologic indicators in patients with acute destructive pancreatitis 42
Gylmiyarova F.N., Shakhnovitch Ye.A., Kolotiyeva N.A., Nefedova N.S., Sidorova I.F., Yepyfanova A.A., Gergel N.I. The evaluation of immunogenetic characteristics of donor blood 42
Dyatlov D.A., Vandysheva M.A., Yarovinsky B.G., Pushkaryev Ye.D., Pushkaryev V.P., Lekontzev Ye.V., Vishnev V.Yu., Degtyarev A.V. The indicators of humoral immunity of hockey players in the conditions of chronic cold adaptation 42
Koshel Ye.O., Dolgushin I.I., Kvyatkovskaya S.V., Markina O.V. The differential count of leucocytes in umbilical blood using the system CytoDiff 43
Kudayeva I.V. The laboratory analysis in allergy diagnostic exemplified by M.A. examination of adolescents 43
Leonova M.A., Zakharova N.B., Slesarenko N.A., Zankina O.V. The biomarkers in standards of laboratory analysis in patients with chronic periodontitis against the background of osteoporosis 43
Ostrovskaya L.Yu., Zakharova N.B., Vorobyev D.V. The placement of molecular markers in the standards of laboratory examination of patients with chronic paradontitis against the background of osteoporosis 43
Piyanzin A.I., Nazarovskaya O.V., Jukova Ye.N., Zaitsev I.F., Belousov V.A., Ivanov Ye.V., Sapkina M.R. The clinical laboratory diagnostics of helminthiasis in multitype children hospital 44
Piyanzin A.I., Nazartchuk Ye.A., Ivanov Ye.V., Antropova P.I., Simonova O.G., Karbyshev I.A., Leschenko V.A. The age-specific characteristics of detecting the allergen specific antibodies class E in children 44
Reshetnikov I.V., Tzeylikman V.E., Kvyatkovskaya S.V. The estimation of the levels of subpopulation of leucocytes in patients with HIV-infection using flow cytometry and system CytoDiff 44
Saygusheva L.A., Nokhrina S.N., Kuyarov A.V., Tchegryntseva Ye.V. The information value of immune status indicators under secondary immune deficient states in children in conditions of North 45
Sysoyeva Yu.G., Psaryeva Ye.K. The occurrence of antigen K of system Kellin male donors serving in the navy: the relationship of the given antigen with blood groups of system AB0 45
Tchistyakova G.N. The possibilities of using the detection of spontaneous and mitogen-induced production of cytokines in clinical practice 45
Tcholyakhyan A.V., Korshunov G.V., Pavlenko N.N., Gladkova Ye.V., Putchinyan D.M., Bluvschtein G.A., Klotchkov M.A. The study of certain non-specific factors of immune defense under osteomyelitis 45
Yarovinsky B.G., Vandysheva M.A. The production of cytokines in the cell culture under prurigo of adults 45
THE STANDARDIZED TECHNOLOGY OF BACTERIOLOGIC ANALYSIS OF URINE  
Menshikov V.V. The standardization of technologies for clinical microbiologic Research 46
Shulyak B.F. The optimization of bacteriologic analysis of urine as provided by international standards 46
Sukhorukova M.V., Palagin I.V., Kozlov R.S. The development of the project of standardized analytical technology «The bacteriological analysis of urine» 47
Kaftyryeva L.A., Makarova M.A., Matveyeva Z.N. The value of enterobacteria in etiology of infections of urinary tracts 47
Dolgikh T.I. The perinatal pathology: potentials of laboratory in bacteriologic analysis of urine 47
Boytsov A.G. The diagnostic criteria of evaluation of the value of bacteriuria 48
Alyeva Ye.V. The evaluation of eff ectiveness of stages of bacteriologic analysis of urine 48
Galeyeva Ye.V., Samarina O.Yu. The experience of application the test system Deep Streak in bacteriologic express-analysis on the stage of standardized technology «Bacteriologic analysis of urine» 48

THE STANDARDIZATION OF MOLECULAR BIOLOGIC METHODS OF DIAGNOSTICS OF SEXUALLY TRANSMITTED INFECTIONS

 
Guschin A.Ye., Shypulin G.A. The characteristics of standardization of molecular methods in diagnostics of sexually transmitted infections 49
Kuyevda D.A., Kireyev D.Ye., Shipulin G.A. The experience of development of standardized trechnology of laboratory analysis of viral load of HIV and viral hepatitis applying molecular biologic technologies 49
Tvorogova M.G. The issues of external evaluation of quality of molecular biologic studies 50

THE STANDARDIZATION OF METHODS OF ANALYSIS OF HEMOSTASIS SYSTEM

 
Dobrovolsky A.B., Titayeva Ye.V. The formation of thrombin and its functions in hemostasis system 50
Vavilova T.V. The algorithm of initial diagnostics of disorders in hemostasis system 50
Andreyeva A.S. The actual strategy of thrombophilia diagnostics 50
Berkovsky A.L., Sergeyeva Ye.V., Suvorov A.V., Kozlov A.A., The pre-analytical stage in hemostasiology 50
Zaikin Ye.V., Dobrovolsky A.B., Kosyrev A.B., Berkovsky A.L., Malakhov V.N. The analytical errors of methods of analysis of hemostasis system according the data of the Federal system of external assessment of quality 51

THE INTERACTION OF CLINIC AND LABORATORY AT THE CENTRALIZATION OF LABORATORY ANALYSIS

 
Dolgikh T.I. The actual issues of organization of functioning of clinical diagnostic laboratories 52
Kishkun A.A. The standardization of pre-analytical stage at the centralization of laboratory analysis 52
Gilmanov A.J. On the pre-analytical requirements to analysis of hemostasis at the centralization of laboratory analysis 52
Skorkhodova T.G., Matushkina S.V. The characteristics of pre-analytical stage in pediatrics 53
Tchernysh N.Yu., Naydenova T.V., Slepysheva V.V., Kozlov A.V. The implementation of policy of critical values in conditions of interdistrict centralized clinical diagnostic laboratory 54
Afonina N.V., Ryjkina L.L., Kulyutsyna Ye.R. The organization of the system of female population target dispenserization on localization of cervix diseases in Penza oblast 54
Dementiyev V.Ye., Kuznetsova Ye.P., Berestovskaya V.S., Kozlov A.V. The implementation of critical values policy in conditions of inter-district centralized clinical diagnostic laboratory 54

THE LIQUID CYTOLOGY AS A STANDARDIZED TECHNOLOGY OF PREPARATIONS’ COMPOSITION

 
Nikitina L.V., Shabalova I.P., Kasoyan K.T., Djangyrova T.V. The immune cytochemical analysis based on the liquid cytologyliquid cytology 55
Voltchenko N.N., Slavnova Ye.N., Tugulukova A.A. The methods of liquid cytology in diagnostics of non-gynecologic material 55

THE LABORATORY DIAGNOSTICS OF ONCOLOGIC DISEASES

 
Delektorskaya V.V. The neuro-endocrinal tumors: epidemiology, nomenclature, laboratory and morphologic diagnostics 56
Sergeyeva N.S., Marshutina N.V., Alentov I.I., Solokhina M.P. The serologic markers CA125 and HE4 in monitoring of patients with disseminated ovarian carcinoma 57
Gershtein Ye.S., Prorokov V.V., Korotkova Ye.A., Delektorskaya V.V., Golovkov D.A., Kushlinsky N.Ye. The prognostic value of tumor-associated proteinases in patients with cancer of colon 57
Ponukalin A.N., Popkov V.M., Zakharova N.B., Mikhaylov V.Yu. The prospectives of inclusion of molecular markers into standards of diagnostics and staging of urinary bladder cancer 58
Korshunov G.V., Pavlenko N.N., Putchinyan D.M., Gladkova Ye.V., Shakhmartova S.G. The cytokines in blood serum of patients with bone tumors 58
Vaschenko A.A., Zaytsev V.G., Ostrovsky O.V., Khvastunov R.A. The detection of content of circulating DNA in blood serum as a basis for development of test of monitoring of course of oncologic diseases 59

THE ISSUE PUBLICATIONS

 
Adjigova R.R., Yermilova V.D., Galdava O.D., Lyakina L.T., Sharashenidze O.T., Manukhin I.B., Laktionov K.P., Kuznetsova O.M., Berezov T.T. The receptors of epidermal growth factor in cancer of endometrium and ovaries 59
Babkina I.V., Russo Ye.Yu., Bulytcheva I.V., Kuznetsov I.N., Soloviyev Yu.N., Ten Ye.A., Aliyev M.D. The soluble form of molecule of adhesion of endothelium of vessels type I (sVCAM-1) under bone tumors 61
Zakharova N.B., Nikolsky Yu.Ye., Ponukalin A.N. The prospective of application of «urine» biomarkers in the standards of examination of patients with kidney cancer 62
Kushlinsky D.N., Levkina N.V., Gershtein Ye.S., Yermilova V.D., Tereshkina I.V., Laktionov K.P., Adamyan L.V. The clinical value of analysis of components VEGF-signal path and matrix metalloproteinases in patients with ovaries neoplasms 62

THE DISCUSSION MATERIALS ON THESES OF MOLECULAR BIOLOGIC RESEARCH

 
Anufriyeva Ye.Ye., Subbotina T.N. On the issue of necessity of control of genome DNA level in test prior to application of polymerase chain reaction testing to detect the allelic polymorphism 64
Bilalov F.S., Aminev R.A., Akhmadullina Yu.A., Gilmanov A.J. On the expedience of implementation into routine practice the analysis of polymorphism of genes of folate cycle in women under pregnancy pathology 64
Krasitskaya V.V., Burakova L.P., Frank L.A., Olkhovsky I.A., Subbotina T.N. The application of и bioluminescent reporters in detection of allelic polymorphism of factor V Leiden 64
Sukhovolskaya M.A., Subbotina T.N., Olkhovsky I.A., Bazarin K.P., The mutations in genes of methylenetetrahydrofolatreductase and methioninesintase and risk factors of hyperhomocysteinemia in athletes 65

THE HEMATOLOGIC STUDIES

 
Zimina V.A., Zenina M.N., Kozlov A.V., Gubarenko N.K. The analysis of liquor under oncologic hematologic diseases 65
Kulyutsyna Ye.R., Savelyev V.P., Glebova O.A., Sorokina L.A. The information value of hematologic indicators in clinical laboratory examination of patients with vascular dementia 65
Lugovskaya S.A., Potchtar M.Ye., Naumova Ye.V., Plekhanova O.S., Kisylytchina D.G., Tsvetayeva N.V., Mikhaylova Ye.V. The evaluation of reticulocytes under paroxysmal night hemoglobinuria using the flow cytofl uorometry 66
Nikitina G.V., Slavinsky A.A. The cyto-chemical markers of activation of neutrophilic leucocytes under hyperthyroidism 66
Potchtar M.Ye., Lugovskaya S.A., Naumova Ye.V., Kisylytchina D.G., Plekhanova O.S., Minenkov A.S. The application of hematologic analyzer ADVIA 2120 for expanded characteristic of erythrocytes in patients with various forms of anemia 66
Rudenko N.N., Bazarin K.P., Olkhovsky I.A., Zykova U.V. The possibilities of automated evaluation of fractions of reticulocytes in practice of medical control of training regimen of athletes 67

THE LABORATORY STUDIES OF HEMOSTASIS SYSTEM

 
Andriyenko A.V., Bublikov D.S. On the issue of counting the number of thrombocytes in patients of rheumatologic profile 68
Akhmadullina Yu.A., Gaysina Yu.R., Idrisova G.A., Gilmanov A.J., Mavzyutov A.R. On the reaction of platelet component on the endotoxicosis associated with bacterial vaginosis 68
Bondar T.P., Muratova A.Yu., Tzaturyan Ye.O. The alteration of indicators of plasma hemostasis in women with thrombo-haemorrhagic complications in obstetrics practice 68
Bondar T.P., Elmesova L.A. The evaluation of functional condition of erythrocytes in diagnostics of hemorheological disorders under diabetes mellitus type 2 69
Zykova U.V., Olkhovsky I.A., Subbotina T.N. The chronometric coagulation tests and parameters of spatial growth of clot in silent carriers of thrombogenic polymorphisms 69
Korshunov G.V., Putchinyan D.M., Shakhmartova S.G. On additional risk criteria of thrombogenic complications under hip replacement 69
Kosyakova Yu.A., Davydkin I.L., Gergel N.I., Selezneva I.A., Nikolayeva O.A. The laboratory criteria for assessing the prognosis of bleeding in patients with hemophilia 70
Kulyutsina Ye.R., Savelyev Sorokina L.A., Glebova O.A. The dynamics of hemostasiologic indicators in patients with vascular dementia 70
Leonov N.P., Karmadonova N.A., Strunin O.V. The laboratory methods of evaluation of hemostasis disorders in children of first year of life with congenital heart disease 70
Olkhovsky I.A., Subbotina T.N., Shaykhutdinova R.V., Shevtsova A.O. The characteristic of optical aggregatometry of thrombocytes in silent carriers of polymorphisms of genes of thrombotic receptors and plasma factors of hemostasis 70
Roytman Ye.V. The medicinal prevention of venous thrombembolia: is the laboratory control needed? 71
Sibiryeva O.F., Kalyujin V.V., Urazova O.I., Kalyujina Ye.V., Kalyujina M.I. The polymorphism of genes of coagulate system in patients with chronic kidney disease 71
Sibiryeva O.F., Kalyujin V.V., Urazova O.I., Kalyujina Ye.V., Kalyujina M.I.,Mylovanova T.A. The markers of dysfunction of endothelium in patients with diabetes mellitus type I with diabetic nephropathy 72
Stolyar M.A., Olkhovsky I.A., Grinshtein Yu.I., Titova N.M. The test of thrombocytes resistance to acetylsalicylic acid in vitro as a predictor of preventive effectiveness of preparation under cardiovascular pathology 72
Titova M.I., Gumargalyeva K.Z., Kashpersky Yu.P., Demidova V.S., Yegorova V.V, Guseynov E.K., Kuznetsova A.G. The evaluation of biologic compatibility and functional characteristics of polymeric materials (implants) of hydrogel on the basis of development of hematologic and cytological standards 72
Shylova A.N. The laboratory control of anti-coagulating prevention during post-operational period in oncological patients 73
Shylova A.N., Karpenko A.A., Karmadonova N.A., Dzemidovitch O.G. The laboratory control of thrombolytic therapy in patients with acute thromboembolism of pulmonary arteries 73

THE BIOCHEMICAL CHARACTERISTICS OF VARIOUS CLINICAL CONDITIONS

 
Belova S.V. The laboratory evaluation of activity of inflammatory process in patients with rheumatoid arthritis 74
Vorobyeva Ye.N., Yefremushkina A.A., Bublikov D.S., Yurkova Yu.V. The new marker of metabolic syndrome 74
Yepifantseva N.N., Borschykova T.I., Tchurlyayev Yu.A., Yekimovskikh A.V., Nagibina Т.В. The value of neopterin in eraly prognosis of outcome of severe cerebral injury 74
Zatchinyaev G.V., Andryukov B.G. The concept of laboratory screening under surgical stress: the analysis of cortisol level in blood 74
Istratov V.G., Demidova V.S., Zviyagin A.A., Rodionova S.S., Kuznetsova A.G., Titova M.I., Ratchenkova N.I., Kutcheynik A.Sh. The chromatographic and biochemical criteria of evaluation of multiple organ failure and possibilities of intratype therapy using pharmaconutrients in patients with severe surgical infection 74
Istratov V.G., Demidova V.S., Ratchenkova N.I., Medova O.V., Kuprin A.V., Bulanova N.M., Nikolayeva O.N., Zviyagin A.A., Kazennov V.V. The chromatographic criteria of pathogenic mechanisms of development of intoxication in patients with surgical infection 75
Kavrayskaya A.Yu., Dorofeytchik-Drygina N.A., Drygina L.B., Prokhorova O.V. The hormones and mineral bone density: the stomatological aspects 75
Kartavenkov S.A., Borisova O.V., Shulyak L.I. The particular laboratory tests in specialized nephrology care: focus on general clinical study of peritoneal effluent with quantitative determination of protein 75
Karyakina Ye.V., Konyutchenko Ye.A., Gladkova Ye.V. The evaluation of peroxidation antioxidant balance in patients in the early acute period of complicated trauma of cervical spine 76
Kopytova T.V., Khimkina L.N., Panteleyeva G.A. The mode of detection of pharmacological resistance in patients with chronic disseminated dermatitis 76
Orlov Ye.N., Golubeva D.v., Ilyzarova E.I. The value of detection of androsteron in urine with the purpose of diagnostic of hyperandrogenism 76
Pashkina I.V., Suplotov S.N. The soluble receptors of transferrin as a modern indicator of standard of diagnostics of ferrum defi ciency condition in children 76
Piyanzin A.I., Bakanov A.A., Nazartchuk Ye.A., Nazarovskaya O.V., Jukova Ye.N., Vanina Ye.A., Zaytsev I.F., Leschenko V.A., Karbyshev I.A., Valova A.G. The experience of laboratory diagnostics of adreno-genital syndrome in children under dynamic physician monitoring 76
Piyanzin A.I., Kolesnikova M.A., Zaytsev I.F., Belousov V.A., Gromova M.I. The clinical diagnostic laboratory services in the Health centers for children 77
Prikhodko M.A., Gladylin G.P., Senotova M.V. The clinical laboratory value of indicators of erythropoiesis andferrum metabolism under chronic pyelonephritis 77
Raygorodskaya N.Yu., Bolotova N.V., Zakharova N.B., Ivanenko I.L. The content of laboratory support in case of detection of retardation of sexual development in boys 77
Rubtsov G.K., Bezrutchko N.V., Vasylkov V.G., Gengin M.T., Diveyeva Ye.Yu., Shirokina A.A., Krivtchenkova Ye.V. The analysis of specters of substances with low and medium molecular weight under cholecystitis in early post operational period 77
Solovyeva A.G., Martusevitch A.K., Peretyagin S.P. The transformation of particular parameters of physical biochemical homeostasis of blood in early period of burn disease 77
Khohlova O.A., Kalayeva G.Yu., Ustyntseva I.M. The indicators of bone metabolism in adolescents 78
Shestopalov A.V., Trofi menko O.V., Shestopalova M.A. The levels of leptin and grelin in blood serum of children with chronic gastroduodenites 78
Shestopalov A.V., Trofimenko O.V., Shestopalova M.A. The level of trefoil peptides (TFF-1 and TFF-2) in children with chronic gastroduodenites 78

THE MICROBIOLOGIC STUDIES IN CLINICAL LABORATORY

 
Andrjukov B.G., Timtchenko N.F. On necessity to expand the standards of laboratory diagnostics of intestinal yersiniasis under epidemic and sporadic morbidity and secondary herdnidal forms of infection 79
Ardatova L.V., Kravetz A.A., Slavogorsky V.S., The diagnostics of HIV-infection with validation by immune bloating reaction 79
Batanina I.A., Zalzman A.G., Vorobyeva Ye.N., Kondakova N.V., Sharapov V.V., Shashev N.S., Tcharova Ye.V. On the issue of laboratory diagnostics of tuberculosis 79
Beloborodova N.V., Voziyan A.Yu., Osipov A.A. The laboratory diagnostics of bacterial intoxication using the technique of gas chromatographic analysis of blood 79
Boyko O.V., Aleksashina L.I., Boyko V.I., Kondrashova Yu.V., Jurikhin A.V., Dotsenko Yu.I. RNA-depended activity of microorganisms 79
Boyko O.V., Dotsenko Yu.I., Boyko V.I., Kondrashova Yu.V., Jurikhin A.V., Aleksashina L.I. The bactericidal activity of sperm of workers of the Astrakhan gas-processing plant 80
Boyko O.V., Nikolayev A.A., Boyko V.I., Kondrashova Yu.V., Jurikhin A.V., Dotsenko Yu.I., Aleksashina L.I. The morphologic alterations of semen plasma under carriage of various types of staphylococcus 80
Boronina L.G., Blinova S.M. The application of screening tests in detection of Streptococcus agalactiae in biomaterials of adult female patients from the perinatal center 80
Boronina L.G., Samatova Ye.V. The study of the role of Streptoccocus pneumoniae in etiology of children infections 80
Vasiliyev Ye.V., Moskov V.I., Olkhovsky I.A., Gorbenko A.S., Strukova Ye.G. The determination of profile of carbonic acids using the technique of gas chromatography and mass-spectrometry to evaluate etiology and intensity of infectious affection of patients with acute leucosis 81
Davletova A.A., Postrigan B.N., Gritsenko V.A., Mavzyutov A.R., The development of the modes of express-evaluation of etiologica value of bacteria of Staphylococcus genus 81
Ilyina V.N., Subbotovskaya A.I., Kozyreva V.S., Shylova A.N. The study of activity of vancomicin concerning S. aureus isolated under infection of sternotomic wound after coronary artery bypass grafting 81
Karpenko S.F. The detection of catalase of blood serum as an additional technique in examination of Q-fever patients 81
Kishkun A.A., Arsenin S.L. The new paradigm for laboratory monitoring of treatment of chronic viral hepatitis C 82
Kropotov V.S., Pyshkina Ye.I., Mishanov V.R. The relevance of the Westernblot method in diagnostics of syphilis 82
Kubanov S.I., Bondar T.P., Kubanova A.B. The indicators of hematologic automated analyzer in evaluation of surgical patients’ condition 82
Lakhtin M.V., Bayrakova A.L., Lakhtin V.M., Afanasyev S.S., Aleshkin V.A. The lektins of probiotics - a new class of signal molecules of quorum esthesia 82
Lakhtin M.V., Bayrakova A.L., Lakhtin V.M., Afanasyev S.S., Aleshkin V.A. The pool of lactobacilla populations as a sensor of biotop status sensitive to the presence of lectins of human probiotic lactobacilla 83
Lakhtin M.V., Lakhtin V.M., Belikova Ye.v., Kulakova Yu.V., Agapova Yu.V., Afanasyev S.S., Aleshkin V.A. The new highly sensitive technique of evaluation of system and major lectins of gram-positive bacteria as exemplified bylactobacilla and bifidobacteria 83
Mironov A.Yu., Mitrokhin S.D., Ardatskaya M.D., Shevtsov V.V., Jakot A.N. The diagnostic and prognostic value of metabolites of microflora in different substrates in patients with lung cancer and chronic obstructive lung disease 83
Mironov A.Yu., Polucarpova S.V., Jylina S.V., Pivkina N.V., Timofeyeva O.G. The monitoring of pathogens of infections of urinary tracts in the resuscitation and intensive therapy unit 84
Mironov A.Yu., Kharseyeva G.G., Mikhailova Ye.A., Jerebyatyeva O.O. The diagnostically valuable characteristics of urogenital microflora in detection of duration of gonorrhea course 84
Myrsayapova I.A., Khasanova G.F., Khazeyeva G.D., Mavzyutov A.R. The development of hightech modes of etiologic molecular diagnostic express- diagnostics of community-acquired pneumonia 85
Petrova L.V., Puzanov V.A. The centralization and effectiveness of laboratory analyses of tuberculosis in the Republic of Mari-El 85
Plakhova K.I., Rotanov S.V., Rakhmatullina M.R., Khayrullin R.F. On the application of immune-enzyme analysis to diagnose the urogenital clamidiosis in women 85
Rotanov S.V., Ermatova F.A. The information value of immune-enzyme analysis IgM in examination of patients with syphilitic infection 86
Terekhina N.A., Reuk S.E., Petrovitch Yu.A. The proteins of mouth liquid during the herpetic infection 86
Tyukavkina S.Yu., Kharseyeva G.G., Vasylyeva G.I. The study of the role of apoptosis in pathogenesis of whooping cough 86
Ustyantseva I.M., Khokhlova O.I., Petukhova O.V., Jevlakova Yu.A. The laboratory diagnostics of pyo-septic complications in patients with polytrauma in critical conditions 86
Frolova Ya.N., Kharseyeva G.G., Mironov A.Yu. The antibiotic resistance of toxigenic strains of C. diphtheriae 86
Kharseyeva G.G., Voronina N.A., Kharisova A.R., Mamytcheva N.I., Golovanova N.A. The pathogenic characteristics of Corynbacterium non diphtheriae 87
Tchиkhlovin A.B., Napalkova O.S., Emanuel Yu.V., Eysmont Yu.A., Emanuel V.L. The possible role of urease producing microorganisms in the genesis of urolithiasis 87
Tscherbataya O.S., Kharseyeva G.G. The antibiotics-resisted strains of E. coli isolated from the respiratory tract in Rostov-on-Don and Rostov oblast 87

THE LABORATORY MARKERS IN TRANSPLANTOLOGY

 
Kuntsevitch N.V., Makarova L.V., Olephirenko G.A., Akhaladze D.G., Tsyrulnikova O.V., Shevtchenko O.P. The level of ceruloplasmin during liver transplantation is related to the intensity of oxidative stress 87
Kuntsevitch N.V., Olephirenko G.A., Akhaladze D.G., Shmerko N.P. Shevtchenko O.P. The level of hepsidin and its relationship with routine laboratory parameters in children with inherent and congenital diseases of hepatobiliary system 88
Kurabekova R.M., Lugovskaya S.A., Naumova Ye.V., Andriyanova A.A., Shevtchenko O.P. The analysis of concentration of hemopoietic stem cells in peripheral blood of children during the liver transplantation and its relationships with routine laboratory parameters 88
Lurye Yu.E., Bugrov A.V., Tsyrulnikova I.Ye., Mnatsakyan D.S., Tsyrulnikova O.M., Shevtchenko O.P. The insulin-like growth factor I during liver transplantation to children with inherent and congenital diseases of hepatobiliary system 88
Olefyrenko G.A., Orlova O.V., Kuntsevitch N.V., Makarova L.V., Kormer A.Ya., Shevtchenko O.P. The homocystein, antibodies to cardiolipin and soluble form of ligand CD40 (sCD40L) in heart recipients 88
Olefyrenko G.A., Tsyrulnikova I.Ye., Pyschulyna M.E., Bugrov A.V., Andriyanova A.A., Schevtchenko O.P. The diagnostic and prognostic value of neopterin and soluble form CD30 (sCD30) in children as liver recipients 88
Shevtchenko O.P., Gytchkun O.Ye., Dolgov V.V., Schmerko N.P., Gotye S.V. The liver transplantation: the role of soluble form of ligand CD40 (sCD40L) and antibodies to HLA 89
Shevtchenko O.P., Kurabekova R.M., Khalliulin T.A., Ilynsky I.M., Kupriyanova A.G., Mironkov B.L. The predictive value of plasma protein A associated with pregnancy and antibodies to HLA in heart recipients 89
Shevtchenko O.P., Khalliulin T.Yu., Orlova O.V., Mironkov B.L., The placental growth factor as a predictor of development of vasculopathy of transplant in heart recipients 89

THE CYTOLOGICAL STUDIES

 
Amineva R.Kh., Imelbayeva E.A., Rutchkin V.N., Khusnutdynov Sh.M., Gylmanov A.J., Mustafi na V.Kh. The actual issues of clinical cytology in the Republic of Bashkortostan 89
Garypova M.Z., Imelbayeva E.A., Gilmanov A.J. The cytological diagnostics of intestine diseases in the system of hi-tech care in central municipal hospital 90
Iskhakova G.S., Imelbayeva E.A., Amineva R.Kh. On the role of centralized cytologic laboratory of central district hospital in the system of medical services provision 90
KuznetsovA.V., Astrakov S.V., Popkova O.V. The mode of detection of metastases of malignant neoplasms in palatine tonsils 90
Sakayeva V.M., Imelbayeva E.A., Gilmanov A.J. On the information value of cytologic diagnostics of liver cancer on the stage of highly specialized medical care 91

THE LABORATORY STUDIES IN TOXICOLOGY

 
Kudayeva I.V., Budarina L.A. The indicators of protein metabolism in vinyl chloride exposed patients 91
Popkova O.V., Masnaviyeva L.B., Kudayeva I.V. The biochemical markers of endothelium dysfunction in patients underwent chronic toxic exposure to mercury 91
Salyakhova R.M., Gazizzulin R.R., Fatkullin K.V., Utarbayeva G.Kh., Gylmanov A.J. The information value of basic laboratory tests under acute intoxication of carbon monoxide 91

THE EXPERIENCE OF PROFESSIONAL ADVANCED TRAINING OF LABORATORY SPECIALISTS

 
Imelbayeva E.A., Amineva R.Kh., Gilmanov A.J., Shtan L.V. The characteristics of education of clinical cytology at the cycles of post-graduate training of physicians of clinical diagnostic laboratory in modern conditions 92
Imelbayeva E.A., Galeyeva L.R., Murzina R.R., Akhtyamova Z.T., Fatkullina A.F., Galiullin D.V., Gilmanov A.J. On the control of quality of detection of immunoglobulin E at the cycle of post-graduate training in allergology and immunology 92
Imelbayeva E.A., Gilmanov A.J., Badretdinova R.T., Khabibullina A.G., Khalykova F.F. On the control of quality of detection of oncomarker CA-125 at cycles of professional advanced training of specialists of clinical diagnostic laboratory 92
Pervushin Yu.V., Frantzeva V.O., Sokhatch A.Ya., Agranovitch N.V. The means of enhancement of quality of training in the system of post-graduate and advanced education 93