Medico-Social Expert Evaluation and Rehabilitation №3 2011

PRIMARY OSTEOPOROSIS: CLINICAL SIGNIFICANCE AND SOCIO-ECONOMIC ASPECTS

I.A. Skripnikova, A.M. Yavisya

According to WHO data osteoporosis (OP) takes the 5th place among the diseases causing damage to public health. Total risk of fractures leading to clinical cases makes approximately 40% and is equivalent to the risk of cardiovascular diseases development. Fracture of the proximal section of thigh-bone is the most serious complication of osteoporosis, in 86% of cases it is associated with intensification of the risk of following fractures and accompanied by the highest rate of disablement and death. In spite of that in a number of countries including Russia osteoporosis is not entered into the list of priority or socially significant diseases. Only due to preventive measures performed within the framework of the governmental program the incidence of new fractures can be significantly diminished.

Key Words:   osteoporosis, fractures, risk factors, socio-economic significance

REFERENCES

1. Михайлов Е. Е., Беневоленская Л. И., Аникин С. Г. и др. Частота остеопоротических переломов основных локализаций среди городского населения России // Науч.-практ. ревматол. — 2001. — № 3. — С. 75.

2. Руководство по остеопорозу / Под ред. Л. И. Беневоленской. — М., 2003.

3. Assessment of Fracture Risk and its Application to Screening for Postmenopausal Osteoporosis. Report of a WHO Study Group. (WHO. Techn. Rep. Ser. N 843). — Geneva, 1994.

4. Blanchard F., President of Report Group. Report on Osteoporosis in the European Community: Building Strong Bones and Preventing Fractures — Action for Prevention. European Communities. — Brussels, 1998.

5. Cooper C. The crippling consequences of fractures and their impact on quality of life // Am. J. Med. — 1997. — Vol. 103, Suppl. 2A. — P. 12—17.

6. Cooper C., Atkinson E. J., O’Fallon W. M. et al. Incidence of clinically diagnosed vertebral fractures: a population — based study in Rochester, Minnesota 1985—1989 // J. Bone Miner. Res. — 2001. — Vol. 7. — P. 221.

7. Delmas P. D. et al. Underdiagnosis of vertebral fractures is a worldwide problem: the impact study // J. Bone Miner. Res. — 2005. — Vol. 20. — P. 557—563.

8. Ellfors L. et al. The variable incidence of hip fracture in Southern Europe: the MEDOC Study // Osteoporos. Int. — 1994. — Vol. 4. — P. 253—263.

9. Felsenberg D. et al. Incidence of vertebral fracture in Europe: results from the European Prospective Osteoporosis Study Epos // J. Bone Miner. Res. — 2002. — Vol. 17. — P. 716—724.

10. Johnell O. et al. The apparent incident of hip fracture in Europe: a study of national registry sources. MEDOC Study Group // Osteoporos. Int. — 1992. — Vol. 2. — P. 298.

11. Jones G. et al. Prevalent vertebral deformities: relationship to bone mineral density and spinal osteophytosis in elderly men and women // Osteoporos. Int. — 1996. — Vol. 6. — P. 233— 239.

12. Kanis J. A. Diagnosis of osteoporosis and assessment of fracture risk // Lancet. — 2002. — Vol. 359. — P. 1829.

13. Kanis J. A., Johnell O. on behalf of the Committee of Scientific Advisors of the International Osteoporosis Foundation. Requirements for DXA for the management of Osteoporosis in Europe // Osteoporos. Int. — 2005. — Vol. 16. — P. 229—238. Адаптировано из Kanis J. A. et al. // J. Bone Miner. Res. — 2002. — Vol. 17. — P. 1237—1244.

14. Kanis J. A. et al. Risk and burden of vertebral fractures in Sweden. Osteoporos. Int. — 2004. — Vol. 5. — P. 20—26.

15. Kanis J. A., Johnell O., De laet C. et al. A meta-analysis of previous fractures and subsequent fracture risk // Bone. — 2004. — Vol. 35. — P. 375.

16. Kanis J. A., Johnell O. Requirements for DXA for the management of osteoporosis in Europe // Osteoporos. Int. — 2005. — Vol. 16. — P. 229—238.

17. Kanis J. A. on behalf of the World Health Organization Scientific group (2007). Technical Report. World Health Organization Collaborating Centre for Metabolic Bone Diseases. — Sheffield, UK, 2007. — P. 24.

18. Lindsay R., Silverman S. L., Cooper C. et al. Risk of new vertebral fracture in the year following a fracture // J. A. M. A. — 2001. — Vol. 285. — P. 320.

19. Magaziner J. et al. Predictors of functional recovery one year following hospital discharge for hip fracture: a prospective study // J. Gerontol. — 1990. — Vol. 45. — P. M101—M107.

20. Melton L. J. III, Amadio P. C., Crowson C. S., O’Fallon W. M. Long-term trends in the incidence of distal forearm fractures / / Osteoporos. Int. — 1998. — Vol. 8. — P. 341.

21. Melton L. J. III. Эпидемиология переломов. — М.; СПб., 2000. — С. 249—272.

22. Mikhailov E., Benevolenskaya L. I., Ershova O. B. Incidence of hip fractures of pirepheral skeletal bones in populational selection of subjects aged 50 years and over // Gerontologija. — 2001. — N 2. — P. 139—145.

23. National osteoporosis Foundation. Osteoporosis: review of the evidence for prevention, diagnosis, and treatment and cost-effectiveness analysis // Osteoporos. Int. — 1998. — Vol. 8, Suppl. 4. — P. S51—S88.

24. Nguyen T. V., Center J. R., Eisman J. A. Osteoporosis: underrated, underdiagnosed and undertreated // Med. J. Aust. — 2004. — Vol. 180. — P. S18.

25. O’Neill T. W., Felsenberg D., Varlow J., The European Vertebral Osteoporosis Study Group. The prevalence of vertebral deformities in European men and women // J. Bone Miner. Res. — 1996. — Vol. 11. — P. 1010—1017.

26. Ray N., Chan J., Thamer M. et al. Medical expenditures for the treatment of osteoporotic fractures in the United States in 1995; Report from the National Osteoporosis Foundation // J. Bone Miner. Res. — 1997. — Vol. 12. — P. 24—34.

27. Resolution WHA51.18. Noncommunicable disease prevention and control // Fifty-first World Health Assembly, Geneva, 11—16 May 1998. — Geneva, 1998.

28. Schurch M.-A., Rizzoli R., Mermilod B. et al. A prospective study on socioeconomic aspects of fracture of the proximal femur // J. Bone Miner. — 1996. — Vol. 11. — P. 1935—1942.

29. The World Health Report 1997: Conquering Suffering, Enriching Humanity. — Geneva, 1997.

30. The World Health Report 2004: Changing History. — Geneva, 2004.